hermes meta analysis|mitchell demchuk : 2024-10-22 In this meta-analysis we, the trial investigators, aimed to pool individual patient data from these trials to address remaining questions about whether the therapy is effi cacious .
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0 · thrombectomy trials
1 · mitchell demchuk
2 · m2 segment occlusion
3 · hermes trial stroke
4 · hermes trial
5 · hermes collaboration stroke
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hermes meta analysis*******Apr 23, 2016 — A systematic review and meta-analysis of randomized controlled trials of endovascular thrombectomy compared with best medical treatment for acute ischemic stroke
Little more than 20 years ago, stroke was widely regarded as an untreatable .
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta .
A network meta-analysis 14 of direct and indirect comparisons of impregnated .
The overlong path to confirming this simple and intuitive treatment plan leads to the .In this meta-analysis we, the trial investigators, aimed to pool individual patient data from these trials to address remaining questions about whether the therapy is effi cacious .Sep 29, 2023 — We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual .Aug 13, 2021 — In a patient-level meta-analysis of randomized controlled EVT trials, we investigate the effects of EVT and reperfusion on cerebral edema and the impact of cerebral edema on functional outcome in .METHODS: We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual .The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of .Apr 23, 2016 — The overlong path to confirming this simple and intuitive treatment plan leads to the HERMES collaboration, the meta-analysis from Mayank Goyal and colleagues—including principal investigators from .Feb 18, 2016 — This pooled analysis of patient-level data suggests that modern endovascular thrombectomy added to best medical therapy more than doubles the odds .Oct 23, 2018 — In the HERMES meta-analyses of the five endovascular trials published in 2015, the median time of onset to reperfusion was 285 min and successful reperfusion .Feb 16, 2021 — Direct comparison of good outcome or mortality after thrombectomy in the NIS cohort with that observed in the five thrombectomy trials (3–7) or their combined meta-analysis as in the HERMES study is .
The HERMES core laboratory identified patients with M2 segment MCA occlusions and further classified them as proximal versus distal, anterior versus posterior division, and dominant versus co-dominant versus non-dominant. Primary outcome was modified Rankin Scale (mRS) score 0-2 at 90 days. . Meta-Analysis MeSH terms Aged .
In this individual patient data meta-analysis of patients with large-vessel ischemic stroke, earlier treatment with endovascular thrombectomy + medical therapy compared with medical therapy alone was associated with lower degrees of disability at 3 months. Benefit became nonsignificant after 7.3 hou .
hermes meta analysis mitchell demchuk%PDF-1.7 %âãÏÓ 18 0 obj > endobj xref 18 39 0000000016 00000 n 0000001388 00000 n 0000001562 00000 n 0000001612 00000 n 0000001671 00000 n 0000002071 00000 n 0000002811 00000 n 0000003962 00000 n 0000004704 00000 n 0000008718 00000 n 0000009179 00000 n 0000009598 00000 n 0000009934 00000 n 0000015662 00000 n .A meta-analysis of penumbral imaging and functional outcome in stroke patients treated with endovascular thrombectomy or medical therapy.
We formed the HERMES collaboration to pool patient-level data from five trials (MR CLEAN, ESCAPE, REVASCAT, SWIFT PRIME, and EXTEND IA) done between December, 2010, and December, 2014. . A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA .
Hermes, MJ and Fry, AC. Intentionally slow concentric velocity resistance exercise and strength adaptations: a meta-analysis. J Strength Cond Res 37(8): e470-e484, 2023-Intentionally slow-velocity resistance exercise (ISVRE) is suggested by some to be equally or more effective than fast or traditional velocities for increasing muscular . The detailed of the HERMES collaboration (The Highly Effective Reperfusion evaluated in Multiple Endovascular Stroke Trials) initiation and the methodology of the meta-analysis search strategy and data gathering has been previously reported. 1,23 The investigators searched PubMed database for randomized controlled trials comparing .and data inclusion (Data Supplement). The meta-analysis was prospectively designed by the HERMES executive committee but not registered. The details of the HERMES collaboration initiation, methodology of meta-analysis search strategy, indi-vidual participant data gathering and checking, and qualitativeand the HERMES meta-analysis are published else-where. In brief, all patients had proximal acLVO other than THRACE that included 2 patients with basilar Nonstandard Abbreviations and Acronyms acLVO anterior circulation large vessel occlusion ASPECTS Alberta Stroke Program Early CT Score CTL control EVT endovascular treatmentarticle (and its online-only Data Supplement). The HERMES (Highly Effective Reperfusion Using Multiple Endovascular Devices) collab-oration is a prospective individual-patient-level meta-analysis done in accordance with PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) of data from 7 major trials:
The treatment approach for acute ischaemic stroke is straightforward: restore blood flow as soon as possible and do it as safely and completely as possible. The overlong path to confirming this simple and intuitive treatment plan leads to the HERMES collaboration, the meta-analysis from Mayank Goyal and colleagues—including . Assuming a similar recovery in the NIS cohort, an estimated 38.6% of patients in the NIS would reach a modified Rankin Scale score of 0–2 at 3 months, which is lower than the 46% who achieved this outcome in the HERMES meta-analysis, albeit equivalent to or better than the 32.6% in the Multicenter Collaboration for Endovascular .hermes meta analysisMethods- Individual patient-level data were combined in this meta-analysis of all patients included in randomized trials comparing endovascular thrombectomy predominantly done with stent retrievers with standard care in anterior circulation ischemic patients with stroke (HERMES [Highly Effective Reperfusion Using Multiple Endovascular Devices .
Methods: In a systematic review and individual patient-level meta-analysis of 7 randomized controlled trials comparing thrombectomy versus medical therapy in anterior circulation ischemic stroke published between January 1, 2010, and May 31, 2017 (Highly Effective Reperfusion Using Multiple Endovascular Devices collaboration), we .
The treatment approach for acute ischaemic stroke is straightforward: restore blood flow as soon as possible and do it as safely and completely as possible. The overlong path to confirming this simple .mitchell demchuk Assuming a similar recovery in the NIS cohort, an estimated 38.6% of patients in the NIS would reach a modified Rankin Scale score of 0–2 at 3 months, which is lower than the 46% who achieved this .Methods- Individual patient-level data were combined in this meta-analysis of all patients included in randomized trials comparing endovascular thrombectomy predominantly done with stent retrievers with standard care in anterior circulation ischemic patients with stroke (HERMES [Highly Effective Reperfusion Using Multiple Endovascular Devices .
Methods: In a systematic review and individual patient-level meta-analysis of 7 randomized controlled trials comparing thrombectomy versus medical therapy in anterior circulation ischemic stroke published between January 1, 2010, and May 31, 2017 (Highly Effective Reperfusion Using Multiple Endovascular Devices collaboration), we .The details of the HERMES collaboration initiation, methodology of meta-analysis search strategy, individual participant data gathering and checking, and qualitative assessment of between-trial differences including patient eligibility and assessment of bias have been previously reported. 1,11 No issues were identified in checking individual . Introduction. Since the landmark randomized trials in 2015 resulting in the HERMES meta-analysis in 2016 endovascular thrombectomy (EVT) has become the standard of care for large vessel occlusion (LVO) strokes in the anterior circulation within a time window of 6 h after onset of symptoms. 1 Whereas these trials demonstrated that . Age groups were defined based on the HERMES meta-analysis, 7 enabling a detailed analysis of patients older than 80 years. Third, clinical and imaging assessments were performed by local investigators at the respective study center and are therefore prone to substantial interrater variability. Fourth, the GSR-ET does not provide information . The five trials included over 1200 patients in total, and their data were combined in the HERMES meta-analysis.7 The researchers of this trial concluded that MT led to significantly better “good functional outcomes,” as defined by a modified Rankin score of 0-2. Patients treated with MT achieved the primary outcome in 46% of participants .abstract = "BACKGROUND AND PURPOSE: Whether reperfusion into infarcted tissue exacerbates cerebral edema has treatment implications in patients presenting with extensive irreversible injury.
In our meta-analysis, high admission SBP was associated with worse functional outcome after stroke, but SBP did not seem to negate the effect of endovascular thrombectomy. This finding suggests that admission SBP should not form the basis for decisions to withhold or delay endovascular thrombectomy for ischaemic stroke, but randomised trials are . However, the treatment benefit with IV tPA or thrombectomy (eg, the difference between treatment and no treatment) is maintained across age despite age’s negative impact on outcome. Indeed, the HERMES meta-analysis showed no significant heterogeneity in treatment effect (90-day mRS shift) across age (P=0.07).
The five trials (table 1) included over 1200 patients in total, and their data were combined in the HERMES meta-analysis. 7 The researchers of this trial concluded that MT led to significantly better “good functional outcomes,” as defined by a modified Rankin score of 0-2. Patients treated with MT achieved the primary outcome in 46% of .
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hermes meta analysis|mitchell demchuk